APOE-Monoclonal Antibodies

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APOE

Qty


Total
$220
Catalog #
A0304
Antibody Type
Polyclonal Antibody
Gene ID
348
Swiss Prot
P02649
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
Reactivity Human Mouse
Tested applications WB IHC
Recommended Dilution WB 1:500 - 1:2000 IHC 1:50 - 1:100
Calculated MW 36kDa
Observed MW Refer to Figures
Immunogen A synthetic peptide of human APOE
Storage Buffer Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym APOE;AD2;LDLCQ5;LPG;MGC1571;
Images
  • A0304: image 1

    Western blot analysis of extracts of various cell lines, using APOE antibody.

  • A0304: image 2

    Immunohistochemistry of paraffin-embedded human prostate using ApoE antibody at dilution of 1:100 (40x lens).

  • A0304: image 3

    Immunohistochemistry of paraffin-embedded human stomach using ApoE antibody at dilution of 1:100 (40x lens).

  • A0304: image 4

    Immunohistochemistry of paraffin-embedded mouse lung using ApoE antibody at dilution of 1:100 (40x lens).

  • A0304: image 5

    Immunohistochemistry of paraffin-embedded human prostate using ApoE antibody at dilution of 1:100 (x40 lens).

  • A0304: image 6

    Immunohistochemistry of paraffin-embedded human prostate using ApoE antibody at dilution of 1:100 (x40 lens).

  • A0304: image 7

    Immunohistochemistry of paraffin-embedded human lung using ApoE antibody at dilution of 1:100 (x40 lens).

Background

The apolipoprotein E(APOE) is a 299-amino acid polypeptide that mediates the binding, internalization, and catabolism of lipoprotein particles, and also serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. The very strong association of the APOE ɛ4 allele with AD risk and its role in the accumulation of amyloid β in brains of people and animal models solidify the biological relevance of apoE isoforms but do not provide mechanistic insight

Protocol

N/A

MSDS
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