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Our customer service representatives are available 24 hours, Monday through Friday to assist you.| Reactivity | Human Mouse |
| Tested applications | WB IHC IF FC |
| Recommended Dilution | WB 1:500 - 1:1000 IHC 1:50 - 1:200 IF 1:20 - 1:50 FC 1:20 - 1:50 |
| Calculated MW | 61kDa |
| Observed MW | Refer to Figures |
| Immunogen | A synthetic peptide of human CDC73 |
| Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | C1orf28; FLJ23316; HPT-JT; HRPT2 |
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]
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