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Our customer service representatives are available 24 hours, Monday through Friday to assist you.| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC IF |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| Calculated MW | 62kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human FBXW11 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | Hos; BTRC2; FBW1B; Fbw11; BTRCP2; FBXW1B; |
Western blot analysis of extracts of various cells, using FBXW11 antibody.
Immunohistochemistry of paraffin-embedded mouse lung using FBXW11 antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of A549 cell using FBXW11 antibody.
Immunofluorescence analysis of A549 cell using FBXW11 antibody.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
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