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Our customer service representatives are available 24 hours, Monday through Friday to assist you.| Reactivity | Human |
| Tested applications | WB |
| Recommended Dilution | WB 1:200 - 1:1000 |
| Calculated MW | 225kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human SCN8A |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
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