APRT Human-Transferase

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APRT Human

Qty


Total
$65
Catalog #
ENPS-494
Size
Description
APRT Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 180 amino acids (1-180 a.a.) and having a molecular mass of 19.6 kDa. The APRT is purified by conventional chromatography.
Additional Information
Introduction APRT is part of the purine/pyrimidine phosphoribosyltransferase family. APRT enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). APRT produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in APRT causes 2,8-dihydroxyadenine urolithiasis. APRT catalyzes a salvage reaction resulting in the formation of AMP.
Synonyms EC 2.4.2.73, MGC125857, AMP diphosphorylase, Adenine phosphoribosyltransferase, APRT, AMP, MGC125856, MGC129961, DKFZp686D13177.
Source Escherichia Coli.
Physical Appearance Sterile Filtered colorless solution.
Formulation The protein solution contains 20mM Tris-HCl pH-8, 1mM DTT and 10% glycerol.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid Sequence MADSELQLVE
QRIRSFPDFP
TPGVVFRDIS
PVLKDPASFR
AAIGLLARHL
KATHGGRIDY
IAGLDSRGFL
FGPSLAQELG
LGCVLIRKRG
KLPGPTLWAS
YSLEYGKAEL
EIQKDALEPG
QRVVVVDDLL
ATGGTMNAAC
ELLGRLQAEV
LECVSLVELT
SLKGREKLAP
VPFFSLLQYE.
Purity Greater than 90.0% as determined by SDS-PAGE.
Usage NeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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