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Our customer service representatives are available 24 hours, Monday through Friday to assist you.| Introduction | Troponin-T is one of three subunits that form the troponin complex of the thin filaments of striated muscle, it regulates muscle contraction in response to alterations in intracellular calcium ion concentration. TnTc is expressed only in the heart and has proved to be a specific biomarker for heart disease. Mutations in TNNT2 are associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Alternative splicing results in many tissue-specific isoforms. |
| Synonyms | Troponin T cardiac muscle, TnTc, Cardiac muscle troponin T, cTnT, TNNT2, CMH2, CMPD2, MGC3889. |
| Source | Human Cardiac Tissue. |
| Physical Appearance | Sterile Filtered colourless liquid formualtion. |
| Formulation | Human Cardiac Troponin T in 6M Urea, 250mM NaCl, 50mM Tris-HCl, 15mM b-mercaptoethanol, 1mM EDTA, pH-7.2. |
| Stability | Human TnT althoµgh stable at 10°C for 7 days, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles. |
| Purity | Greater than 98.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
| Usage | NeoBiolab's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals. |
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