UROD Human-Decarboxylase

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UROD Human

Qty


Total
$65
Catalog #
ENPS-543
Size
Description
UROD Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 387 amino acids (1-367 a.a.) and having a molecular mass of 43 kDa. The UROD is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
Introduction UROD is the fifth enzyme in the human heme biosynthetic pathway and is in charge for the transfer of uroporphyrinogen to coproporphyrinogen throµgh the deletion of four carboxymethyl side chains. UROD Mutations and deficiency result in 3 autosomal disorders in humans: familial porphyria cutanea tarda (f-PCT), sporadic porphyria cutanea tarda (s-PCT) and hepatoerythropoietic porphyria (HEP).
Synonyms UPD, PCT, EC 4.1.1.37, URO-D, UROD, Uroporphyrinogen Decarboxylase.
Source Escherichia Coli.
Physical Appearance Sterile filtered colorless solution.
Formulation UROD Human solution containing 20mM Trsi pH-8, 1mM DTT, 0.1M NaCl, 1mM EDTA & 20% glycerol.
Stability UROD Human althoµgh stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Amino Acid Sequence MGSSHHHHHH
SSGLVPRGSH
MEANGLGPQG
FPELKNDTFL
RAAWGEETDY
TPVWCMRQAG
RYLPEFRETR
AAQDFFSTCR
SPEACCELTL
QPLRRFPLDA
AIIFSDILVV
PQALGMEVTM
VPGKGPSFPE
PLREEQDLER
LRDPEVVASE
LGYVFQAITL
TRQRLAGRVP
LIGFAGAPWT
LMTYMVEGGG
SSTMAQAKRW
LYQRPQASHQ
LLRILTDALV
PYLVGQVVAG
AQ
Purity Greater than 95.0% as determined by SDS-PAGE.
Usage NeoBiolab's products are furnished forLABORATORY RESEARCHUSEONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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